Immunogen sequence: MTESASSTSG QEFDVFSVMD WKDGVGTLPG SDLKFRVNEF GALEVITDEN EMENVKKATA TTTWMVPTAQ EVFSEKTGMP FRLKDPVKVE GLQFCENCCQ YGNVDECLSG GNYCSQNCAR HIKDKDQKEE RDVEEDNEEE DPKCSRKKKP KLSLKADTKE DGEERDDEME NKQDVRILRG SQRARRKRRG DSAVLKQGLP PKGKKAWCWA SYLEEEKAVA VPAKLFKEHQ; Positive Samples: HeLa, 293T, U-251MG, Mouse spleen; Cellular Location: Nucleus
BPGM belongs to the phosphoglycerate mutase family, BPG-dependent PGAM subfamily. It plays a major role in regulating hemoglobin oxygen affinity as a consequence of controlling 2, 3-BPG concentration. It can also catalyze the reaction of EC 220.127.116.11 (mutase) and EC 18.104.22.168 (phosphatase), but with a reduced activity.
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Protein Aliases: H-l(3)mbt-like protein 3; L(3)mbt-like protein 3; Lethal(3)malignant brain tumor-like protein 3; MBT-1
Gene Aliases: AI481284; KIAA1798; L3MBTL3; MBT-1; MBT1