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Invitrogen
LACTB2 Polyclonal Antibody
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FIGURE: 1 / 5
LACTB2 Antibody (PA5-100598) in ICC/IF
Immunocytochemistry analysis of LACTB2 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with LACTB2 polyclonal antibody (Product # PA5-100598) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-100598
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human LACTB2(Accession Q53H82), corresponding to amino acid residues D126-D176.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total LACTB.
Target Information
Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta-lactamase-like protein 2; Endoribonuclease LACTB2; lactamase, beta 2; testicular secretory protein Li 23
Gene Aliases: CGI-83; E430032H21Rik; LACTB2
UniProt ID: (Human) Q53H82, (Rat) Q561R9, (Mouse) Q99KR3
Entrez Gene ID: (Human) 51110, (Rat) 297768, (Mouse) 212442
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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