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Proteintech
LAMB1 Polyclonal Antibody
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Product Details
23498-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LAMB1 Fusion Protein Ag19182 (1437-1786 aa encoded by BC113455)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: AHNAWQKAM DLDQDVLSAL AEVEQLSKMV SEAKLRADEA KQSAEDILLK TNATKEKMDK SNEELRNLIK QIRNFLTQDS ADLDSIEAVA NEVLKMEMPS TPQQLQNLTE DIRERVESLS QVEVILQHSA ADIARAEMLL EEAKRASKSA TDVKVTADMV KEALEEAEKA QVAAEKAIKQ ADEDIQGTQN LLTSIESETA ASEETLFNAS QRISELERNV EELKRKAAQN SGEAEYIEKV VYTVKQSAED VKKTLDGELD EKYKKVENLI AKKTEESADA RRKAEMLQNE AKTLLAQANS KLQLLKDLER KYEDNQRYLE DKAQELARLE GEVRSLLKDI SQKVAVYSTC L (1437-1786 aa encoded by BC113455)
Target Information
Laminins are large heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma chains. They are ubiquitously present in basement membrane (BM) along with entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: laminin B1; Laminin B1 chain; laminin B1 subunit 1; laminin beta 1; Laminin subunit beta-1; laminin, beta 1; Laminin-1 subunit beta; Laminin-10 subunit beta; Laminin-12 subunit beta; Laminin-2 subunit beta; Laminin-6 subunit beta; Laminin-8 subunit beta; MGC142015; unnamed protein product
Gene Aliases: C77966; C80098; C81607; CLM; D130003D08Rik; Lamb-1; LAMB1; Lamb1-1; LIS5
UniProt ID: (Human) P07942, (Mouse) P02469
Entrez Gene ID: (Human) 3912, (Mouse) 16777, (Rat) 298941
cell adhesion
negative regulation of cell adhesion
embryo implantation
anatomical structure morphogenesis
cell migration
neuronal-glial interaction involved in cerebral cortex radial glia guided migration
positive regulation of cell migration
neuron projection development
substrate adhesion-dependent cell spreading
endodermal cell differentiation
odontogenesis
positive regulation of cell adhesion
positive regulation of epithelial cell proliferation
positive regulation of muscle cell differentiation
regulation of basement membrane organization
positive regulation of integrin-mediated signaling pathway
learning or memory
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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