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Proteintech
LANCL1 Polyclonal Antibody
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Product Details
12647-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LANCL1 Fusion Protein Ag3361 (100-399 aa encoded by BC028685)
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TKRSITFLC GDAGPLAVAA VLYHKMNNEK QAEDCITRLI HLNKIDPHAP NEMLYGRIGY IYALLFVNKN FGVEKIPQSH IQQICETILT SGENLARKRN FTAKSPLMYE WYQEYYVGAA HGLAGIYYYL MQPSLQVSQG KLHSLVKPSV DYVCQLKFPS GNYPPCIGDN RDLLVHWCHG APGVIYMLIQ AYKVFREEKY LCDAYQCADV IWQYGLLKKG YGLCHGSAGN AYAFLTLYNL TQDMKYLYRA CKFAEWCLEY GEHGCRTPDT PFSLFEGMAG TIYFLADLLV PTKARFPAFE L (100-399 aa encoded by BC028685)
Target Information
NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention. Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 40 kDa erythrocyte membrane protein; G protein-coupled receptor 69; G protein-coupled receptor 69A; Glutathione S-transferase LANCL1; LanC (bacterial lantibiotic synthetase component C)-like 1; LanC (bacterial lantibiotic synthetase component); LanC lantibiotic synthetase component C-like 1; LanC-like protein 1; p40
Gene Aliases: AW124738; Gpr69; GPR69A; LANCL1; p40
UniProt ID: (Human) O43813, (Mouse) O89112
Entrez Gene ID: (Human) 10314, (Mouse) 14768
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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