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LAP3 Polyclonal Antibody

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Antibody Testing Data (9)

LAP3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 9

LAP3 Antibody (14612-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human gliomas tissue slide using 14612-1-AP ( LAP3 antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

Product Image Gallery

LAP3 Antibody in Western Blot (WB) — Mouse spleen tissue were subjected to SDS PAGE followed by western blot with 14612-1-AP (LAP3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

Product Details

14612-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

LAP3 Fusion Protein Ag6205 (271-519 aa encoded by BC065564)

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Product Specific Information

Immunogen sequence: NANEPPLVF VGKGITFDSG GISIKASANM DLMRADMGGA ATICSAIVSA AKLNLPINII GLAPLCENMP SGKANKPGDV VRAKNGKTIQ VDNTDAEGRL ILADALCYAH TFNPKVILNA ATLTGAMDVA LGSGATGVFT NSSWLWNKLF EASIETGDRV WRMPLFEHYT RQVVDCQLAD VNNIGKYRSA GACTAAAFLK EFVTHPKWAH LDIAGVMTNK DEVPYLRKGM TGRPTRTLIE FLLRFSQDNA (271-519 aa encoded by BC065564)

Target Information

Leucine Aminopeptidase 3 (LAP3) is involved in the processing and regular turnover of intracellular proteins. It catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. Release of an N-terminal amino acid, Xaa-/-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but reated on arylamides are exceedingly low.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Proteomic Analysis of Hepatocellular Carcinoma Tissues With Encapsulation Shows Up-regulation of Leucine Aminopeptidase 3 and Phosphoenolpyruvate Carboxykinase 2.

Cancer genomics & proteomics

Kuhara K,Kitagawa T,Baron B,Tokuda K,Sakamoto K,Nagano H,Nakamura K,Kobayashi M,Nagayasu H,Kuramitsu Y

Fri Dec 03 00:00:00 EST 2021

2,2',4,4'-Tetrabromodiphenyl ether disrupts spermatogenesis, impairs mitochondrial function and induces apoptosis of early leptotene spermatocytes in rats.

Reproductive toxicology (Elmsford, N.Y.)

Huang S,Cui Y,Guo X,Wang L,Li S,Lu Y,Bi Y,Huang X,Lin M,Xia Y,Wang S,Wang X,Zhou Z,Sha J

Thu Jan 01 00:00:00 EST 2015

2,2',4,4'-Tetrabromodiphenyl ether disrupts spermatogenesis, impairs mitochondrial function and induces apoptosis of early leptotene spermatocytes in rats.

Reproductive toxicology (Elmsford, N.Y.)

Huang S,Cui Y,Guo X,Wang L,Li S,Lu Y,Bi Y,Huang X,Lin M,Xia Y,Wang S,Wang X,Zhou Z,Sha J

Thu Jan 01 00:00:00 EST 2015

The alteration of protein profile induced by cigarette smoking via oxidative stress in mice epididymis.

The international journal of biochemistry & cell biology

Zhu Z,Xu W,Dai J,Chen X,Zhao X,Fang P,Yang F,Tang M,Wang Z,Wang L,Ma D,Qaio Z

Fri Mar 01 00:00:00 EST 2013

The alteration of protein profile induced by cigarette smoking via oxidative stress in mice epididymis.

The international journal of biochemistry & cell biology

Zhu Z,Xu W,Dai J,Chen X,Zhao X,Fang P,Yang F,Tang M,Wang Z,Wang L,Ma D,Qaio Z

Fri Mar 01 00:00:00 EST 2013

Bioinformatics

Protein Aliases: Cysteinylglycine-S-conjugate dipeptidase; Cytosol aminopeptidase; epididymis secretory protein Li 106; LAP; LAP-3; Leucine aminopeptidase 3; Leucyl aminopeptidase; peptidase 7; Peptidase S; Proline aminopeptidase; Prolyl aminopeptidase

Gene Aliases: 2410015L10Rik; AA410100; HEL-S-106; LAP; LAP-3; LAP3; LAPEP; Pep-7; Pep-S; Pep7; PEPS

UniProt ID: (Human) P28838, (Rat) Q68FS4, (Mouse) Q9CPY7

Entrez Gene ID: (Human) 51056, (Rat) 289668, (Mouse) 66988

Molecular Function: metalloprotease