FIGURE: 1 / 9
Immunogen sequence: NANEPPLVF VGKGITFDSG GISIKASANM DLMRADMGGA ATICSAIVSA AKLNLPINII GLAPLCENMP SGKANKPGDV VRAKNGKTIQ VDNTDAEGRL ILADALCYAH TFNPKVILNA ATLTGAMDVA LGSGATGVFT NSSWLWNKLF EASIETGDRV WRMPLFEHYT RQVVDCQLAD VNNIGKYRSA GACTAAAFLK EFVTHPKWAH LDIAGVMTNK DEVPYLRKGM TGRPTRTLIE FLLRFSQDNA (271-519 aa encoded by BC065564)
Leucine Aminopeptidase 3 (LAP3) is involved in the processing and regular turnover of intracellular proteins. It catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. Release of an N-terminal amino acid, Xaa-/-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but reated on arylamides are exceedingly low.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cysteinylglycine-S-conjugate dipeptidase; Cytosol aminopeptidase; epididymis secretory protein Li 106; LAP; LAP-3; Leucine aminopeptidase 3; Leucyl aminopeptidase; peptidase 7; Peptidase S; Proline aminopeptidase; Prolyl aminopeptidase
Gene Aliases: 2410015L10Rik; AA410100; HEL-S-106; LAP; LAP-3; LAP3; LAPEP; Pep-7; Pep-S; Pep7; PEPS
Molecular Function: metalloprotease