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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:2,000-1:10,000 | - |
Immunoprecipitation (IP) |
Assay-dependent | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Between 1350 and 1400 |
Conjugate |
Unconjugated |
Form |
liquid |
Concentration |
1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
tris citrate/phosphate, pH 7-8 |
Contains |
0.09% sodium azide |
Storage conditions |
4° C |
The recommended shelf life for this product is 1 year from date of receipt.
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: leukemia-associated rho guanine nucleotide exchange factor; Leukemia-associated RhoGEF; Rho guanine nucleotide exchange factor (GEF) 12; Rho guanine nucleotide exchange factor 12
Gene Aliases: ARHGEF12; KIAA0382; LARG; PRO2792
UniProt ID: (Human) Q9NZN5
Entrez Gene ID: (Human) 23365
Molecular Function:
guanyl-nucleotide exchange factor
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