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LASP1 Polyclonal Antibody

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Antibody Testing Data (21)

LASP1 Antibody in Immunocytochemistry (ICC/IF)

LASP1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 21

LASP1 Antibody (10515-1-AP) in ICC/IF

Immunofluorescent analysis of Hela cells, using LASP1 antibody 10515-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

LASP1 Antibody in Immunocytochemistry (ICC/IF)

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

LASP1 Antibody in Western Blot (WB)

LASP1 Antibody in Western Blot (WB)

LASP1 Antibody in Western Blot (WB)

LASP1 Antibody in Western Blot (WB)

LASP1 Antibody in Western Blot (WB)

LASP1 Antibody in Western Blot (WB)

LASP1 Antibody in Western Blot (WB)

LASP1 Antibody in Western Blot (WB)

LASP1 Antibody in Western Blot (WB)

LASP1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

LASP1 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of Hela cells, using LASP1 antibody 10515-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using 10515-1-AP (LASP1 antibody) at dilution of 1:50 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using 10515-1-AP (LASP1 antibody) at dilution of 1:50 (under 10x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using 10515-1-AP (LASP1 antibody) at dilution of 1:50 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using 10515-1-AP (LASP1 antibody) at dilution of 1:50 (under 10x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using 10515-1-AP (LASP1 antibody) at dilution of 1:50 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using 10515-1-AP (LASP1 antibody) at dilution of 1:50 (under 10x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human breast cancer using 10515-1-AP (LASP1 antibody) at dilution of 1:100 (under 10x lens).

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human breast cancer using 10515-1-AP (LASP1 antibody) at dilution of 1:100 (under 40x lens).

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human colon cancer using 10515-1-AP (LASP1 antibody) at dilution of 1:100 (under 40x lens).

LASP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human colon cancer using 10515-1-AP (LASP1 antibody) at dilution of 1:100 (under 10x lens).

LASP1 Antibody in Western Blot (WB) — Various lysates were subjected to SDS PAGE followed by western blot with (Product # 10515-1-AP) LASP1 antibody at dilution of 1:10,000 incubated at room temperature for 1.5 hours.

LASP1 Antibody in Western Blot (WB) — Mouse brain tissue were subjected to SDS PAGE followed by western blot with 10515-1-AP (LASP1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

LASP1 Antibody in Western Blot (WB) — Mouse brain tissue were subjected to SDS PAGE followed by western blot with 10515-1-AP (LASP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

LASP1 Antibody in Western Blot (WB) — MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with 10515-1-AP (LASP1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

LASP1 Antibody in Western Blot (WB) — MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with 10515-1-AP (LASP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

LASP1 Antibody in Western Blot (WB) — SGC-7901 cells were subjected to SDS PAGE followed by western blot with 10515-1-AP (LASP1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

LASP1 Antibody in Western Blot (WB) — PC-3 cells were subjected to SDS PAGE followed by western blot with 10515-1-AP (LASP1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

LASP1 Antibody in Western Blot (WB) — MCF7 cells were subjected to SDS PAGE followed by western blot with 10515-1-AP (LASP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

LASP1 Antibody in Western Blot (WB) — MCF7 cells were subjected to SDS PAGE followed by western blot with 10515-1-AP (LASP1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

LASP1 Antibody in Immunoprecipitation (IP) — IP result of anti-LASP1 (IP: 10515-1-AP, 4 µg; Detection: 10515-1-AP 1:1500) with rat brain tissue lysate 4000 µg.

Product Details

10515-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 23 publications 23 publications

Immunohistochemistry (IHC)

-

View 12 publications 12 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

-

Immunocytochemistry (ICC/IF)

1:10-1:100

View 7 publications 7 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 5 publications 5 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

LASP1 Fusion Protein Ag0800 (125-210 aa encoded by BC012460)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.44 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: EFEKSRMGP SGGEGMEPER RDSQDGSSYR RPLEQQQPHH IPTSAPVYQQ PQQQPVAQSY GGYKEPAAPV SIQRSAPGGG GKRYRAA (125-210 aa encoded by BC012460 )

Target Information

This gene encodes a member of a LIM protein subfamily characterized by a LIM motif and a domain of Src homology region 3. The encoded protein functions as an actin-binding protein and possibly in cytoskeletal organization.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Hepatitis B virus X protein increases LASP1 SUMOylation to stabilize HER2 and facilitate hepatocarcinogenesis.

International journal of biological macromolecules

You H,Yuan D,Li Q,Zhang N,Kong D,Yu T,Liu X,Liu X,Zhou R,Kong F,Zheng K,Tang R

Tue Jan 31 00:00:00 EST 2023

Hepatitis B virus X protein increases LASP1 SUMOylation to stabilize HER2 and facilitate hepatocarcinogenesis.

International journal of biological macromolecules

You H,Yuan D,Li Q,Zhang N,Kong D,Yu T,Liu X,Liu X,Zhou R,Kong F,Zheng K,Tang R

Tue Jan 31 00:00:00 EST 2023

Hepatitis B virus X protein increases LASP1 SUMOylation to stabilize HER2 and facilitate hepatocarcinogenesis.

International journal of biological macromolecules

You H,Yuan D,Li Q,Zhang N,Kong D,Yu T,Liu X,Liu X,Zhou R,Kong F,Zheng K,Tang R

Tue Jan 31 00:00:00 EST 2023

Hepatitis B virus X protein increases LASP1 SUMOylation to stabilize HER2 and facilitate hepatocarcinogenesis.

International journal of biological macromolecules

You H,Yuan D,Li Q,Zhang N,Kong D,Yu T,Liu X,Liu X,Zhou R,Kong F,Zheng K,Tang R

Tue Jan 31 00:00:00 EST 2023

Hepatitis B virus X protein increases LASP1 SUMOylation to stabilize HER2 and facilitate hepatocarcinogenesis.

International journal of biological macromolecules

You H,Yuan D,Li Q,Zhang N,Kong D,Yu T,Liu X,Liu X,Zhou R,Kong F,Zheng K,Tang R

Tue Jan 31 00:00:00 EST 2023

Hepatitis B virus X protein increases LASP1 SUMOylation to stabilize HER2 and facilitate hepatocarcinogenesis.

International journal of biological macromolecules

You H,Yuan D,Li Q,Zhang N,Kong D,Yu T,Liu X,Liu X,Zhou R,Kong F,Zheng K,Tang R

Tue Jan 31 00:00:00 EST 2023

Hepatitis B virus X protein increases LASP1 SUMOylation to stabilize HER2 and facilitate hepatocarcinogenesis.

International journal of biological macromolecules

You H,Yuan D,Li Q,Zhang N,Kong D,Yu T,Liu X,Liu X,Zhou R,Kong F,Zheng K,Tang R

Tue Jan 31 00:00:00 EST 2023

Hepatitis B virus X protein increases LASP1 SUMOylation to stabilize HER2 and facilitate hepatocarcinogenesis.

International journal of biological macromolecules

You H,Yuan D,Li Q,Zhang N,Kong D,Yu T,Liu X,Liu X,Zhou R,Kong F,Zheng K,Tang R

Tue Jan 31 00:00:00 EST 2023

Systematic identification of ALK substrates by integrated phosphoproteome and interactome analysis.

Life science alliance

Adachi J,Kakudo A,Takada Y,Isoyama J,Ikemoto N,Abe Y,Narumi R,Muraoka S,Gunji D,Hara Y,Katayama R,Tomonaga T

Mon Aug 01 00:00:00 EDT 2022

Network pharmacology and experimental analysis to reveal the mechanism of Dan-Shen-Yin against endothelial to mesenchymal transition in atherosclerosis.

Frontiers in pharmacology

Hong M,Wu Y,Zhang H,Gu J,Chen J,Guan Y,Qin X,Li Y,Cao J

Tue Sep 13 00:00:00 EDT 2022

Global mapping of Salmonella enterica-host protein-protein interactions during infection.

Cell host & microbe

Walch P,Selkrig J,Knodler LA,Rettel M,Stein F,Fernandez K,Viéitez C,Potel CM,Scholzen K,Geyer M,Rottner K,Steele-Mortimer O,Savitski MM,Holden DW,Typas A

Wed Aug 11 00:00:00 EDT 2021

Up-regulated microRNA-218-5p ameliorates the damage of dopaminergic neurons in rats with Parkinson's disease via suppression of LASP1.

Brain research bulletin

Ma X,Zhang H,Yin H,Geng S,Liu Y,Liu C,Zhao J,Liu Y,Wang X,Wang Y

Fri Jan 01 00:00:00 EST 2021

CCT8 recovers WTp53-suppressed cell cycle evolution and EMT to promote colorectal cancer progression.

Oncogenesis

Liao Q,Ren Y,Yang Y,Zhu X,Zhi Y,Zhang Y,Chen Y,Ding Y,Zhao L

Fri Dec 03 00:00:00 EST 2021

CCT8 recovers WTp53-suppressed cell cycle evolution and EMT to promote colorectal cancer progression.

Oncogenesis

Liao Q,Ren Y,Yang Y,Zhu X,Zhi Y,Zhang Y,Chen Y,Ding Y,Zhao L

Fri Dec 03 00:00:00 EST 2021

CCT8 recovers WTp53-suppressed cell cycle evolution and EMT to promote colorectal cancer progression.

Oncogenesis

Liao Q,Ren Y,Yang Y,Zhu X,Zhi Y,Zhang Y,Chen Y,Ding Y,Zhao L

Fri Dec 03 00:00:00 EST 2021

CCT8 recovers WTp53-suppressed cell cycle evolution and EMT to promote colorectal cancer progression.

Oncogenesis

Liao Q,Ren Y,Yang Y,Zhu X,Zhi Y,Zhang Y,Chen Y,Ding Y,Zhao L

Fri Dec 03 00:00:00 EST 2021

HSP90-dependent PUS7 overexpression facilitates the metastasis of colorectal cancer cells by regulating LASP1 abundance.

Journal of experimental & clinical cancer research : CR

Song D,Guo M,Xu S,Song X,Bai B,Li Z,Chen J,An Y,Nie Y,Wu K,Wang S,Zhao Q

Fri May 14 00:00:00 EDT 2021

HSP90-dependent PUS7 overexpression facilitates the metastasis of colorectal cancer cells by regulating LASP1 abundance.

Journal of experimental & clinical cancer research : CR

Song D,Guo M,Xu S,Song X,Bai B,Li Z,Chen J,An Y,Nie Y,Wu K,Wang S,Zhao Q

Fri May 14 00:00:00 EDT 2021

HSP90-dependent PUS7 overexpression facilitates the metastasis of colorectal cancer cells by regulating LASP1 abundance.

Journal of experimental & clinical cancer research : CR

Song D,Guo M,Xu S,Song X,Bai B,Li Z,Chen J,An Y,Nie Y,Wu K,Wang S,Zhao Q

Fri May 14 00:00:00 EDT 2021

ECHS1, an interacting protein of LASP1, induces sphingolipid-metabolism imbalance to promote colorectal cancer progression by regulating ceramide glycosylation.

Cell death & disease

Li R,Hao Y,Wang Q,Meng Y,Wu K,Liu C,Xu L,Liu Z,Zhao L

Wed Oct 06 00:00:00 EDT 2021

ECHS1, an interacting protein of LASP1, induces sphingolipid-metabolism imbalance to promote colorectal cancer progression by regulating ceramide glycosylation.

Cell death & disease

Li R,Hao Y,Wang Q,Meng Y,Wu K,Liu C,Xu L,Liu Z,Zhao L

Wed Oct 06 00:00:00 EDT 2021

ECHS1, an interacting protein of LASP1, induces sphingolipid-metabolism imbalance to promote colorectal cancer progression by regulating ceramide glycosylation.

Cell death & disease

Li R,Hao Y,Wang Q,Meng Y,Wu K,Liu C,Xu L,Liu Z,Zhao L

Wed Oct 06 00:00:00 EDT 2021

LIM and SH3 protein 1 localizes to the leading edge of protruding lamellipodia and regulates axon development.

Molecular biology of the cell

Pollitt SL,Myers KR,Yoo J,Zheng JQ

Sun Nov 15 00:00:00 EST 2020

LIM and SH3 protein 1 localizes to the leading edge of protruding lamellipodia and regulates axon development.

Molecular biology of the cell

Pollitt SL,Myers KR,Yoo J,Zheng JQ

Sun Nov 15 00:00:00 EST 2020

Identification of Novel microRNA Profiles Dysregulated in Plasma and Tissue of Abdominal Aortic Aneurysm Patients.

International journal of molecular sciences

Plana E,Gálvez L,Medina P,Navarro S,Fornés-Ferrer V,Panadero J,Miralles M

Sun Jun 28 00:00:00 EDT 2020

LASP1 interacts with N-WASP to activate the Arp2/3 complex and facilitate colorectal cancer metastasis by increasing tumour budding and worsening the pattern of invasion.

Oncogene

Yan P,Liu J,Zhou R,Lin C,Wu K,Yang S,Yang S,Zhou J,Xu L,Wang H,Zhao L

Sat Aug 01 00:00:00 EDT 2020

LASP1 interacts with N-WASP to activate the Arp2/3 complex and facilitate colorectal cancer metastasis by increasing tumour budding and worsening the pattern of invasion.

Oncogene

Yan P,Liu J,Zhou R,Lin C,Wu K,Yang S,Yang S,Zhou J,Xu L,Wang H,Zhao L

Sat Aug 01 00:00:00 EDT 2020

LncRNA NEAT1 Knockdown Inhibits Retinoblastoma Progression by miR-3619-5p/LASP1 Axis.

Frontiers in genetics

Chen X,Zhao S,Li Q,Xu C,Yu Y,Ge H

Tue Dec 08 00:00:00 EST 2020

Calcium Channel Blocker Nifedipine Suppresses Colorectal Cancer Progression and Immune Escape by Preventing NFAT2 Nuclear Translocation.

Cell reports

Wu L,Lin W,Liao Q,Wang H,Lin C,Tang L,Lian W,Chen Z,Li K,Xu L,Zhou R,Ding Y,Zhao L

Tue Oct 27 00:00:00 EDT 2020

p21-activated kinase 4 promotes the progression of esophageal squamous cell carcinoma by targeting LASP1.

Molecular carcinogenesis

Huang H,Xue Q,Du X,Cui J,Wang J,Cheng D,Li J,Zheng Y,Huang G,Zhang K,Liu K,Lu J,Zhao J,Chen X,Dong Z,Li X

Tue Dec 01 00:00:00 EST 2020

p21-activated kinase 4 promotes the progression of esophageal squamous cell carcinoma by targeting LASP1.

Molecular carcinogenesis

Huang H,Xue Q,Du X,Cui J,Wang J,Cheng D,Li J,Zheng Y,Huang G,Zhang K,Liu K,Lu J,Zhao J,Chen X,Dong Z,Li X

Tue Dec 01 00:00:00 EST 2020

Upregulation and hypomethylation of lncRNA AFAP1‑AS1 predicts a poor prognosis and promotes the migration and invasion of cervical cancer.

Oncology reports

Bo H,Fan L,Gong Z,Liu Z,Shi L,Guo C,Li X,Liao Q,Zhang W,Zhou M,Xiang B,Li X,Li G,Xiong W,Zeng Z,Cao K,Zhang S,Xiong F

Mon Apr 01 00:00:00 EDT 2019

ANLN-induced EZH2 upregulation promotes pancreatic cancer progression by mediating miR-218-5p/LASP1 signaling axis.

Journal of experimental & clinical cancer research : CR

Wang A,Dai H,Gong Y,Zhang C,Shu J,Luo Y,Jiang Y,Liu W,Bie P

Thu Aug 08 00:00:00 EDT 2019

ANLN-induced EZH2 upregulation promotes pancreatic cancer progression by mediating miR-218-5p/LASP1 signaling axis.

Journal of experimental & clinical cancer research : CR

Wang A,Dai H,Gong Y,Zhang C,Shu J,Luo Y,Jiang Y,Liu W,Bie P

Thu Aug 08 00:00:00 EDT 2019

LASP1 promotes glioma cell proliferation and migration and is negatively regulated by miR-377-3p.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Liu Y,Gao Y,Li D,He L,Iw L,Hao B,Chen X,Cao Y

Sat Dec 01 00:00:00 EST 2018

LASP1 promotes glioma cell proliferation and migration and is negatively regulated by miR-377-3p.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Liu Y,Gao Y,Li D,He L,Iw L,Hao B,Chen X,Cao Y

Sat Dec 01 00:00:00 EST 2018

LASP1 promotes glioma cell proliferation and migration and is negatively regulated by miR-377-3p.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Liu Y,Gao Y,Li D,He L,Iw L,Hao B,Chen X,Cao Y

Sat Dec 01 00:00:00 EST 2018

LASP1 promotes glioma cell proliferation and migration and is negatively regulated by miR-377-3p.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Liu Y,Gao Y,Li D,He L,Iw L,Hao B,Chen X,Cao Y

Sat Dec 01 00:00:00 EST 2018

Change in distribution of cytoskeleton-associated proteins, lasp-1 and palladin, during uterine receptivity in the rat endometrium.

Reproduction, fertility, and development

Nicholson L,Lindsay L,Murphy CR

Mon Oct 01 00:00:00 EDT 2018

Change in distribution of cytoskeleton-associated proteins, lasp-1 and palladin, during uterine receptivity in the rat endometrium.

Reproduction, fertility, and development

Nicholson L,Lindsay L,Murphy CR

Mon Oct 01 00:00:00 EDT 2018

Change in distribution of cytoskeleton-associated proteins, lasp-1 and palladin, during uterine receptivity in the rat endometrium.

Reproduction, fertility, and development

Nicholson L,Lindsay L,Murphy CR

Mon Oct 01 00:00:00 EDT 2018

Change in distribution of cytoskeleton-associated proteins, lasp-1 and palladin, during uterine receptivity in the rat endometrium.

Reproduction, fertility, and development

Nicholson L,Lindsay L,Murphy CR

Mon Oct 01 00:00:00 EDT 2018

Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway.

Journal of experimental & clinical cancer research : CR

Lian Y,Xiong F,Yang L,Bo H,Gong Z,Wang Y,Wei F,Tang Y,Li X,Liao Q,Wang H,Zhou M,Xiang B,Wu X,Li Y,Li X,Chen X,Li G,Guo C,Zeng Z,Xiong W

Tue Oct 16 00:00:00 EDT 2018

Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway.

Journal of experimental & clinical cancer research : CR

Lian Y,Xiong F,Yang L,Bo H,Gong Z,Wang Y,Wei F,Tang Y,Li X,Liao Q,Wang H,Zhou M,Xiang B,Wu X,Li Y,Li X,Chen X,Li G,Guo C,Zeng Z,Xiong W

Tue Oct 16 00:00:00 EDT 2018

LASP-1 induces proliferation, metastasis and cell cycle arrest at the G2/M phase in gallbladder cancer by down-regulating S100P via the PI3K/AKT pathway.

Cancer letters

Li Z,Chen Y,Wang X,Zhang H,Zhang Y,Gao Y,Weng M,Wang L,Liang H,Li M,Zhang F,Zhao S,Liu S,Cao Y,Shu Y,Bao R,Zhou J,Liu X,Yan Y,Zhen L,Dong Q,Liu Y

Mon Mar 28 00:00:00 EDT 2016

LASP-1 induces proliferation, metastasis and cell cycle arrest at the G2/M phase in gallbladder cancer by down-regulating S100P via the PI3K/AKT pathway.

Cancer letters

Li Z,Chen Y,Wang X,Zhang H,Zhang Y,Gao Y,Weng M,Wang L,Liang H,Li M,Zhang F,Zhao S,Liu S,Cao Y,Shu Y,Bao R,Zhou J,Liu X,Yan Y,Zhen L,Dong Q,Liu Y

Mon Mar 28 00:00:00 EDT 2016

LASP-1 induces proliferation, metastasis and cell cycle arrest at the G2/M phase in gallbladder cancer by down-regulating S100P via the PI3K/AKT pathway.

Cancer letters

Li Z,Chen Y,Wang X,Zhang H,Zhang Y,Gao Y,Weng M,Wang L,Liang H,Li M,Zhang F,Zhao S,Liu S,Cao Y,Shu Y,Bao R,Zhou J,Liu X,Yan Y,Zhen L,Dong Q,Liu Y

Mon Mar 28 00:00:00 EDT 2016

LASP-1 induces proliferation, metastasis and cell cycle arrest at the G2/M phase in gallbladder cancer by down-regulating S100P via the PI3K/AKT pathway.

Cancer letters

Li Z,Chen Y,Wang X,Zhang H,Zhang Y,Gao Y,Weng M,Wang L,Liang H,Li M,Zhang F,Zhao S,Liu S,Cao Y,Shu Y,Bao R,Zhou J,Liu X,Yan Y,Zhen L,Dong Q,Liu Y

Mon Mar 28 00:00:00 EDT 2016

LASP-1 induces proliferation, metastasis and cell cycle arrest at the G2/M phase in gallbladder cancer by down-regulating S100P via the PI3K/AKT pathway.

Cancer letters

Li Z,Chen Y,Wang X,Zhang H,Zhang Y,Gao Y,Weng M,Wang L,Liang H,Li M,Zhang F,Zhao S,Liu S,Cao Y,Shu Y,Bao R,Zhou J,Liu X,Yan Y,Zhen L,Dong Q,Liu Y

Mon Mar 28 00:00:00 EDT 2016

The tumor-suppressive function of miR-1 by targeting LASP1 and TAGLN2 in esophageal squamous cell carcinoma.

Journal of gastroenterology and hepatology

Du YY,Zhao LM,Chen L,Sang MX,Li J,Ma M,Liu JF

Mon Feb 01 00:00:00 EST 2016

The tumor-suppressive function of miR-1 by targeting LASP1 and TAGLN2 in esophageal squamous cell carcinoma.

Journal of gastroenterology and hepatology

Du YY,Zhao LM,Chen L,Sang MX,Li J,Ma M,Liu JF

Mon Feb 01 00:00:00 EST 2016

The tumor-suppressive function of miR-1 by targeting LASP1 and TAGLN2 in esophageal squamous cell carcinoma.

Journal of gastroenterology and hepatology

Du YY,Zhao LM,Chen L,Sang MX,Li J,Ma M,Liu JF

Mon Feb 01 00:00:00 EST 2016

The tumor-suppressive function of miR-1 by targeting LASP1 and TAGLN2 in esophageal squamous cell carcinoma.

Journal of gastroenterology and hepatology

Du YY,Zhao LM,Chen L,Sang MX,Li J,Ma M,Liu JF

Mon Feb 01 00:00:00 EST 2016

Upregulated LASP-1 correlates with a malignant phenotype and its potential therapeutic role in human cholangiocarcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Zhang H,Li Z,Chu B,Zhang F,Zhang Y,Ke F,Chen Y,Xu Y,Liu S,Zhao S,Liang H,Weng M,Wu X,Li M,Wu W,Quan Z,Liu Y,Zhang Y,Gong W

Wed Jun 01 00:00:00 EDT 2016

Upregulated LASP-1 correlates with a malignant phenotype and its potential therapeutic role in human cholangiocarcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Zhang H,Li Z,Chu B,Zhang F,Zhang Y,Ke F,Chen Y,Xu Y,Liu S,Zhao S,Liang H,Weng M,Wu X,Li M,Wu W,Quan Z,Liu Y,Zhang Y,Gong W

Wed Jun 01 00:00:00 EDT 2016

Upregulated LASP-1 correlates with a malignant phenotype and its potential therapeutic role in human cholangiocarcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Zhang H,Li Z,Chu B,Zhang F,Zhang Y,Ke F,Chen Y,Xu Y,Liu S,Zhao S,Liang H,Weng M,Wu X,Li M,Wu W,Quan Z,Liu Y,Zhang Y,Gong W

Wed Jun 01 00:00:00 EDT 2016

Upregulated LASP-1 correlates with a malignant phenotype and its potential therapeutic role in human cholangiocarcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Zhang H,Li Z,Chu B,Zhang F,Zhang Y,Ke F,Chen Y,Xu Y,Liu S,Zhao S,Liang H,Weng M,Wu X,Li M,Wu W,Quan Z,Liu Y,Zhang Y,Gong W

Wed Jun 01 00:00:00 EDT 2016

Epigenetically regulated miR-145 suppresses colon cancer invasion and metastasis by targeting LASP1.

Oncotarget

Wang W,Ji G,Xiao X,Chen X,Qin WW,Yang F,Li YF,Fan LN,Xi WJ,Huo Y,Wen WH,Yang AG,Wang T

Tue Oct 18 00:00:00 EDT 2016

Epigenetically regulated miR-145 suppresses colon cancer invasion and metastasis by targeting LASP1.

Oncotarget

Wang W,Ji G,Xiao X,Chen X,Qin WW,Yang F,Li YF,Fan LN,Xi WJ,Huo Y,Wen WH,Yang AG,Wang T

Tue Oct 18 00:00:00 EDT 2016

MicroRNA-218 inhibits the proliferation, migration, and invasion and promotes apoptosis of gastric cancer cells by targeting LASP1.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Wang LL,Wang L,Wang XY,Shang D,Yin SJ,Sun LL,Ji HB

Tue Nov 01 00:00:00 EDT 2016

AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Zeng Z,Bo H,Gong Z,Lian Y,Li X,Li X,Zhang W,Deng H,Zhou M,Peng S,Li G,Xiong W

Fri Jan 01 00:00:00 EST 2016

AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Zeng Z,Bo H,Gong Z,Lian Y,Li X,Li X,Zhang W,Deng H,Zhou M,Peng S,Li G,Xiong W

Fri Jan 01 00:00:00 EST 2016

Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.

Oncotarget

Bo H,Gong Z,Zhang W,Li X,Zeng Y,Liao Q,Chen P,Shi L,Lian Y,Jing Y,Tang K,Li Z,Zhou Y,Zhou M,Xiang B,Li X,Yang J,Xiong W,Li G,Zeng Z

Fri Aug 21 00:00:00 EDT 2015

Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.

Oncotarget

Bo H,Gong Z,Zhang W,Li X,Zeng Y,Liao Q,Chen P,Shi L,Lian Y,Jing Y,Tang K,Li Z,Zhou Y,Zhou M,Xiang B,Li X,Yang J,Xiong W,Li G,Zeng Z

Fri Aug 21 00:00:00 EDT 2015

Bioinformatics

Protein Aliases: LASP-1; lasp1 {ECO:0000312|RGD:68408}; LIM and SH3 domain protein 1; Metastatic lymph node gene 50 protein; MLN 50; Tg(11Col1a1)NG

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Gene Aliases: AA408629; Def-4; Lasp-1; LASP1; MLN50; SH3P6; Tg(Col1a1-lacZ)1Ngma

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UniProt ID: (Human) Q14847, (Mouse) Q61792, (Rat) Q99MZ8

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Entrez Gene ID: (Human) 3927, (Mouse) 16796, (Rat) 29278

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SH3/SH2 adaptor activity protein binding zinc ion binding ion transmembrane transporter activity actin filament binding cadherin binding involved in cell-cell adhesion actin binding metal ion binding

Process(es)

ion transport positive regulation of signal transduction ion transmembrane transport cell-cell adhesion transport

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