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          • Primary Antibodies ›
          • Lamin B Receptor Antibodies

          Abnova

          LBR Recombinant Rabbit Monoclonal Antibody

          View all (9) Lamin B Receptor antibodies

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          Cite LBR Recombinant Rabbit Monoclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          LBR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          LBR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          LBR Antibody (RAB02144) in IHC (P)

          Immunohistochemical staining (Formalin/PFA-fixed paraffin-embedded sections) of human lung cancer with LBR recombinant monoclonal antibody, clone R04-5H4 (Product # RAB02144). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          LBR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          LBR Antibody in Western Blot (WB)

          Product Details

          RAB02144

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:100
          -

          Immunoprecipitation (IP)

          1:20
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Expression System

          CHO cells

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide corresponding to human LBR.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Purification

          Affinity chromatography

          Storage buffer

          50mM tris glycine, pH 7.4, with 150mM NaCl, 0.05% BSA, 40% glycerol

          Contains

          0.01% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: 3-beta-hydroxysterol Delta (14)-reductase; C-14 sterol reductase; C14SR; Delta(14)-sterol reductase LBR; Delta-14-SR; FLJ43126; Integral nuclear envelope inner membrane protein; Lamin-B receptor; LMN2R; MGC9041; PRO0650; Sterol C14-reductase; tudor domain containing 18; unnamed protein product

          View more View less

          Gene Aliases: C14SR; DHCR14B; LBR; LMN2R; PHA; PHASK; TDRD18

          View more View less

          UniProt ID: (Human) Q14739

          View more View less

          Entrez Gene ID: (Human) 3930

          View more View less

          Function(s)
          DNA binding RNA binding protein binding lamin binding oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor delta14-sterol reductase activity chromo shadow domain binding NADPH binding chromatin-protein adaptor activity
          Process(es)
          lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process steroid metabolic process cholesterol metabolic process sterol biosynthetic process neutrophil differentiation random inactivation of X chromosome
          It has to be done as per old AB suggested Products section.

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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