PA5-32055 targets LCMT2 in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-32055 immunogen is recombinant fragment corresponding to a region within amino acids 317 and 646 of Human LCMT2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW).
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Protein Aliases: Leucine carboxyl methyltransferase 2; p21WAF1/CIP1 promoter-interacting protein; PPM2; tRNA wybutosine-synthesizing protein 4; tRNA wybutosine-synthesizing protein 4 homolog; tRNA yW-synthesizing protein 4; tRNA yW-synthesizing protein 4 homolog; tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase; tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase; tRNA-Wybutosine-synthesizing protein 4; tRNA-yW synthesizing protein 4; TYW4
Gene Aliases: D330024M17; KIAA0547; LCMT2; PPM2; TYW4