This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 8
Immunogen sequence: MATLKEKLIA PVAEEEATVP NNKITVVGVG QVGMACAISI LGKSLADELA LVDVLEDKLK GEMMDLQHGS LFLQTPKIVA DKDYSVTANS KIVVVTAGVR QQEGESRLNL VQRNVNVFKF IIPQIVKYSP DCIIIVVSNP VDILTYVTWK LSGLPKHRVI GSGCNLDSAR FRYLMAEKLG IHPSSCHGWI LGEHGDSSVA VWSGVNVAGV SLQELNPEMG TDNDSENWKE VHKMVVESAY EVIKLKGYTN WAIGLSVADL IESMLKNLSR IHPVSTMVKG MYGIENEVFL SLPCILNARG LTSVINQKLK DDEVAQLKKS ADTLWDIQKD LKDL; Positive Samples: HeLa, A-431, Jurkat, A-549, Mouse brain, Mouse kidney, Mouse heart, Mouse lung, Rat brain; Cellular Location: Cytoplasm
This gene encodes an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on the X chromosome and on chromosome. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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Protein Aliases: epididymis secretory protein Li 281; L-lactate dehydrogenase B chain; lactate dehydrogenase H chain; Lactate dehydrogenease B; LDH heart subunit; LDH-B; LDH-H; LDHH; Renal carcinoma antigen NY-REN-46; testicular secretory protein Li 25
Gene Aliases: AI790582; H-Ldh; HEL-S-281; Ldh-2; LDH-B; LDH-H; Ldh2; LDHB; LDHBD; TRG-5
Molecular Function: dehydrogenase