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Product Details
PA5-53048
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human LEPREL1. Recombinant protein control fragment (Product #RP-89684).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2643345
Product Specific Information
Immunogen sequence: ANPEHMEMQQ NIENYRATAG VEALQLVDRE AKPHMESYNA GVKHYEADDF EMAIRHFEQA LREYFVEDTE CRTLCEGPQR FEEYEYLGYK AGLYEAIADH YMQVLVCQHE CV^M
^M
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.
Target Information
This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: leprecan-like 1; Leprecan-like protein 1; Myxoid liposarcoma-associated protein 4; procollagen-proline 3-dioxygenase 2; Prolyl 3-hydroxylase 2; prolyl 3-hydroxylase 3
Gene Aliases: LEPREL1; MCVD; MLAT4; P3H2
UniProt ID: (Human) Q8IVL5
Entrez Gene ID: (Human) 55214
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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