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Bethyl Laboratories
LETM1 Polyclonal Antibody
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FIGURE: 1 / 2
LETM1 Antibody (A305-558A) in WB
Detection of human LETM1 by western blot. Samples: Whole cell lysate (15 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-LETM1 antibody (Product # A305-558A) (lot A305-558A-1) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds.
Product Details
A305-558A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 625 to 675 of human LETM1 and EF-hand domain-containing protein 1, mitochondrial.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Electroneutral mitochondrial K(+)/H(+)exchanger; KHE; LETM1 and EF-hand domain-containing protein 1, mitochondrial; leucine zipper-EF-hand containing transmembrane protein 1; Leucine zipper-EF-hand-containing transmembrane protein 1; Mdm38 homolog; Mitochondrial proton/calcium exchanger protein; unnamed protein product
Gene Aliases: CONDMIM; KHE; LETM1; Mdm38; SLC55A1
UniProt ID: (Human) O95202
Entrez Gene ID: (Human) 3954
ion transport
potassium ion transport
calcium ion transport
mitochondrial calcium ion transport
mitochondrion organization
inner mitochondrial membrane organization
protein hexamerization
cristae formation
protein homooligomerization
mitochondrial calcium ion homeostasis
negative regulation of mitochondrial calcium ion concentration
calcium export from the mitochondrion
mitochondrial potassium ion transmembrane transport
regulation of cellular hyperosmotic salinity response
hydrogen ion transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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