|Immunohistochemistry (Paraffin) (IHC (P))||12 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 19 amino acid peptide from C-terminus of human RXFP1.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan (100%) Gibbon, Monkey (95%) Marmoset (84%).
LGR7 is a low density lipoprotein receptor of 757 amino acid belonging to the G-protein coupled receptor 1 family with rhodopsin-like receptor activity. It has seven transmembrane region, cysteine-rich motif, 10 LRR domains and 5 N-glycosylation sites in the N terminus. Research reports show that it has receptor for relaxins (RLN1 and RLN2) which stimulates adenylate cyclase activation, substrate adhesion, and chemo migratory capacity of mononuclear leukocytes. LGR7 is critical for mediating these biological responses by use of RNA interference lentiviral short hairpin constructs. It is widely expressed in 86% of 15 primary EC tissue samples including brain, kidney, testis and endometrium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: leucine-rich repeat-containing G protein-coupled receptor 7; Leucine-rich repeat-containing G-protein coupled receptor 7; LGR7; LGR7.1; LGR7.10; LGR7.2; Relaxin family peptide receptor 1; Relaxin receptor 1; relaxin/insulin-like family peptide receptor 1; RXFP1; RXFPR1
Gene Aliases: LGR7; RXFP1; RXFPR1
UniProt ID: (Human) Q9HBX9
Entrez Gene ID: (Human) 59350
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