Immunogen sequence: AGLTRLSLA YLPVKVIPSQ AFRGLNEVIK IEISQIDSLE RIEANAFDNL LNLSEILIQN TKNLRYIEPG AFINLPRLKY LSICNTGIRK FPDVTKVFSS ESNFILEICD NLHITTIPGN AFQGMNNESV TLKLYGNGFE EVQSHAFNGT TLTSLELKEN VHLEKMHNGA FR (49-219 aa encoded by BC157028)
LHCGR encodes the receptor for both luteinizing hormone and choriogonadotropin. It is family 1 of G-protein coupled receptors, FSH/LSH/TSH superfamily, and its basic function is acting as luteinizing hormone/choriogonadotropin receptor (gonadotropin receptor). Regulating the development and function of Leyding cells in males. It also plays a role in male secondary sexual characterdevelopment. Mutations in this gonadotropinreceptor results in disorders of male secondary sexual characteristic development, such as familial male precocious puperty and male pseudohermaphtoditism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HCG receptor; hypergonadotropic hypogonadism; LH/CG-R; LHR; LSH-R; Luteinizing hormone receptor; Lutropin receptor; Lutropin-choriogonadotropic hormone receptor; lutropin/choriogonadotropin receptor
Gene Aliases: Gpcr19-rs1; HHG; LCGR; LGR2; LH-R; LH/CG-R; LH/CGR; LHCGR; LHR; LHRHR; LSH-R; ULG5
Molecular Function: G-protein coupled receptor