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LHX2 Polyclonal Antibody
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FIGURE: 1 / 1
LHX2 Antibody (BS-11200R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded mouse brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with LHX2 Polyclonal Antibody, Unconjugated (bs-11200R) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DA... View More
Product Details
BS-11200R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Goat,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human LHX2, amino acids 251-330.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Homeobox protein LH-2; LIM homeo box protein 2; LIM homeobox protein 2; LIM HOX gene 2; LIM/homeobox protein Lhx2; MGC138390; unnamed protein product
Gene Aliases: ap; apterous; hLhx2; Lh-2; LH2; LH2A; LHX2; Lim2
UniProt ID: (Human) P50458, (Mouse) Q9Z0S2
Entrez Gene ID: (Goat) 102185664, (Human) 9355, (Mouse) 16870, (Rat) 296706
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
protein binding
sequence-specific DNA binding
metal ion binding
transcription factor activity, RNA polymerase II transcription factor binding
zinc ion binding
helix-turn-helix transcription factor
homeodomain transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
neural tube closure
hair follicle development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
nervous system development
axon guidance
brain development
mesoderm development
dorsal/ventral pattern formation
telencephalon development
olfactory bulb development
telencephalon regionalization
cerebral cortex development
neurogenesis
neuron differentiation
maintenance of epithelial cell apical/basal polarity
negative regulation of gene expression, epigenetic
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
anatomical structure formation involved in morphogenesis
axon extension
negative regulation of neurogenesis
retina development in camera-type eye
positive regulation of neural precursor cell proliferation
transcription, DNA-templated
transcription from RNA polymerase II promoter
negative regulation of transcription regulatory region DNA binding
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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