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Invitrogen
LHX4 Polyclonal Antibody
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Product Details
PA5-76338
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein of human LHX4.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in control of differentiation and development of the pituitary gland. Mutations in this gene are associated with syndromic short stature and pituitary and hindbrain defects. An alternative splice variant has been described but its biological nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: LHX4; LIM homeo box protein 4; LIM homeobox protein 4; LIM/homeobox protein Lhx4
Gene Aliases: A330062J17Rik; CPHD4; Gsh-4; Gsh4; LHX4
UniProt ID: (Human) Q969G2, (Mouse) P53776
Entrez Gene ID: (Human) 89884, (Mouse) 16872, (Rat) 360858
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
protein binding
zinc ion binding
methyl-CpG binding
sequence-specific DNA binding
metal ion binding
sequence-specific double-stranded DNA binding
molecular_function
helix-turn-helix transcription factor
homeodomain transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
placenta development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
apoptotic process
motor neuron axon guidance
organ morphogenesis
medial motor column neuron differentiation
neuron differentiation
negative regulation of apoptotic process
positive regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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