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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • LIAS Antibodies

          Invitrogen

          LIAS Polyclonal Antibody

          View all (8) LIAS antibodies

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          Cite LIAS Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (3)
          LIAS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          LIAS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          LIAS Antibody (PA5-118032) in IHC (P)

          Immunohistochemical staining of human LIAS in human brain with LIAS Polyclonal Antibody (Product # PA5-118032, 1:100 dilution, formalin-fixed paraffin embedded sections). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          LIAS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          LIAS Antibody in Western Blot (WB)
          LIAS Antibody in Immunoprecipitation (IP)

          Product Details

          PA5-118032

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunoprecipitation (IP)

          1-5 µL/mg of lysate
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          E. coli-derived Human LIAS fragment

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography, Protein A

          Storage buffer

          PBS, pH 7

          Contains

          0.03% ProClin 300

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2902636

          Target Information

          LIAS belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis.The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: LIAS; lip-syn; Lipoate synthase; Lipoic acid synthase; Lipoyl synthase, mitochondrial; LS; MGC23245

          View more View less

          Gene Aliases: HGCLAS; HUSSY-01; LAS; LIAS; LIP1; LS; PDHLD

          View more View less

          UniProt ID: (Human) O43766

          View more View less

          Entrez Gene ID: (Human) 11019

          View more View less

          Function(s)
          lipoate synthase activity metal ion binding 4 iron, 4 sulfur cluster binding
          Process(es)
          neural tube closure inflammatory response response to oxidative stress lipoate biosynthetic process protein lipoylation response to lipopolysaccharide glyoxylate metabolic process
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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