Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MTPILTVLI CLGLSLGPRT HVQAGHLPKP TLWAEPGSVI IQGSPVTLRC QGSLQAEEYH LYRENKSASW VRRIQEPGKN GQFPIPSITW EHAGRYHCQY YSHNHSSEYS DPLELVVTGA YSKPTLSALP SPVVTLGGNV TLQCVSQVAF DGFILCKEGE DEHPQRLNSH SHARGWSWAI FSVGPVSPSR RWSYRCYAYD SNSPYVWSLP SDLLELLVPG VSKKPSLSVQ PGPMVAPGES LTLQCVSDVG YDRFVLYKEG ERDFLQRPGW QPQAGLSQAN FTLGPVSPSH GGQYRCYSAH NLSSEWSAPS DPLDILITGQ FYDRPSLSVQ PVPTVAPGKN VTLLCQSRGQ FHTFLLTKEG AGHPPLHLRS EHQAQQNQAE FRMGPVTSAH VGTYRCYSSL S (1-400 aa encoded by BC017412)
Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (LILRB1; MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with trans membrane regions containing a charged arginine residue, may initiate stimulatory cascades. One member of subfamily A (LILRA3; MIM 604818) lacks a transmembrane region and is presumed to be a soluble receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD85 antigen-like family member H; CD85h; ILT-1; Immunoglobulin-like transcript 1; leucocyte Ig-like receptor A2; Leukocyte immunoglobulin-like receptor 7; Leukocyte immunoglobulin-like receptor subfamily A member 2; leukocyte immunoglobulin-like receptor subfamily A member 2 soluble; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2; LIR-7
Gene Aliases: CD85H; ILT1; LILRA2; LIR-7; LIR7
UniProt ID: (Human) Q8N149
Entrez Gene ID: (Human) 11027
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support