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Invitrogen
LILRB4 Polyclonal Antibody
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FIGURE: 1 / 1
LILRB4 Antibody (PA5-98762) in WB
Western Blot analysis of LILRB4 using a LILRB4 Polyclonal antibody (Product # PA5-98762) at a concentration of 4.39 µg/mL. Positive WB detected in A549 whole cell lysate. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:10,000 dilution. Observed band size: 50 kDa.
Product Details
PA5-98762
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Leukocyte immunoglobulin-like receptor subfamily B member 4 protein (22-259AA)
Conjugate
Form
Liquid
Concentration
4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B4; CD85 antigen-like family member K; CD85k; ILT-3; Immunoglobulin-like transcript 3; leucocyte Ig-like receptor B4; Leukocyte immunoglobulin-like receptor 5; Leukocyte immunoglobulin-like receptor subfamily B member 4; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4; LIR-5; Monocyte inhibitory receptor HM18
Gene Aliases: CD85K; ILT-3; ILT3; LILRB4; LIR-5; LIR5
UniProt ID: (Human) Q8NHJ6
Entrez Gene ID: (Human) 11006
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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