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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 114 and 381 of Human LILRB5|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28006 targets LILRB5 in WB applications and shows reactivity with Human samples.
The PA5-28006 immunogen is recombinant fragment corresponding to a region within amino acids 114 and 381 of Human LILRB5.
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD85 antigen-like family member C; CD85C; leucocyte Ig-like receptor B5; leukocyte immunoglobulin-like receptor 8; leukocyte immunoglobulin-like receptor subfamily B member 5; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5; LIR-8; LIR8
CD85C; LILRB5; LIR-8; LIR8