Suggested positive control: human muscle tissue, human skeletal muscle protein.
The LIM motif defines a zinc-binding domain that is found in a variety of transcriptional regulators and proto-oncogenes products. LIM domain mediates protein-protein interactions and, with LIM-homeodomain proteins, act as negative regulators of the transcriptional activation function of the protein. This transcription factor is required for embryonic survival and for the determination of many cell types.
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Protein Aliases: hLim-1; Homeobox protein Lim-1; LIM homeobox protein 1; LIM-1; LIM/homeobox protein Lhx1; LIM1; MGC126723; MGC138141
Gene Aliases: LHX1; LIM-1; LIM1
UniProt ID: (Human) P48742
Entrez Gene ID: (Human) 3975