Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 5
Recommended positive controls: 293T, mouse brain.
Predicted reactivity: Mouse (99%), Rat (99%), Xenopus laevis (81%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The Zyxin family of proteins contains five members: Ajuba, Limd1, LPP, TRIP6 and Zyxin. Limd1 (LIM domain-containing protein 1) is a ubiquitously expressed tumor suppressor containing three LIM zinc-binding domains. LIM domains consist of a cysteine-rich consensus sequence containing two distinct zinc-binding subdomains, which mediate protein-protein interactions. Limd1 interacts with the proteins SQSTM1, Rb, p62 and TRAF6. Limd1 was first identified when the deletion of its gene was noted in some cervical cancers. Limd1 blocks in vitro and in vivo tumor growth and is downregulated in lung cancer.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: LIM domain-containing protein 1
Gene Aliases: AW822033; D9Ertd192e; LIMD1
UniProt ID: (Human) Q9UGP4, (Mouse) Q9QXD8
Entrez Gene ID: (Human) 8994, (Mouse) 29806
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