Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
LIN7B Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
12732-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LIN7B Fusion Protein Ag3437 (1-207 aa encoded by BC027618)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAALVEPLG LERDVSRAVE LLERLQRSGE LPPQKLQALQ RVLQSRFCSA IREVYEQLYD TLDITGSAEI RAHATAKATV AAFTASEGHA HPRVVELPKT DEGLGFNIMG GKEQNSPIYI SRVIPGGVAD RHGGLKRGDQ LLSVNGVSVE GEQHEKAVEL LKAAQGSVKL VVRYTPRVLE EMEARFEKMR SARRRQQHQS YSSLESRG (1-207 aa encoded by BC027618)
Target Information
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. May increase the amplitude of ACCN3 acid-evoked currents by stabilizing the channel at the cell surface.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: hLin7B; hVeli2; lin 7 homolog b; lin-7 homolog B; lin-7-A; Lin-7B; MALS-2; Mammalian lin-seven protein 2; Protein lin-7 homolog B; Veli-2; veli-2 protein; vertebrate homolog of C. elegans Lin-7 type 2; Vertebrate lin-7 homolog 2
Gene Aliases: LIN-7B; LIN7B; MALS-2; MALS2; UNQ3116/PRO10200; Veli1a; VELI2
UniProt ID: (Human) Q9HAP6, (Rat) Q9Z252, (Mouse) O88951
Entrez Gene ID: (Human) 64130, (Rat) 60377, (Mouse) 22342
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support