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Abnova
LIPG Polyclonal Antibody, MaxPab™
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Product Details
H00009388-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LIPG (AAH60825.1, 1 a.a. approximately 500 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSNSVPLLCF WSLCYCFAAG SPVPFGPEGR LEDKLHKPKA TQTEVKPSVR FNLRTSKDPE HEGCYLSVGH SQPLEDCSFN MTAKTFFIIH GWTMSGIFEN WLHKLVSALH TREKDANVVV VDWLPLAHQL YTDAVNNTRV VGHSIARMLD WLQEKDDFSL GNVHLIGYSL GAHVAGYAGN FVKGTVGRIT GLDPAGPMFE GADIHKRLSP DDADFVDVLH TYTRSFGLSI GIQMPVGHID IYPNGGDFQP GCGLNDVLGS IAYGTITEVV KCEHERAVHL FVDSLVNQDK PSFAFQCTDS NRFKKGICLS CRKNRCNSIG YNAKKMRNKR NSKMYLKTRA GMPFRVYHYQ MKIHVFSYKN MGEIEPTFYV TLYGTNADSQ TLPLEIVERI EQNATNTFLV YTEEDLGDLL KIQLTWEGAS QSWYNLWKEF RSYLSQPRNP GRELNIRRIR VKSGETQRKL TFCTEDPENT SISPGQELWF RKCRDGWRMK NETSPTVELP
Target Information
LIPG (Lipase G, Endohelial type) is an endothelial lipase which is a novel member of the lipoprotein lipase gene family. LIPG is synthesized by endothelial cells and functions at the site of synthesis. LIPG most likely plays a physiological role in modulating lipoprotein metabolism. Overexpressed LIPG has been shown to reduce HDL cholesterol levels, whereas an LIPG deficiency appears to be effective in elevating HDL cholesterol levels in animals. LIPG has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. Also, LIPG is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. LIPG is a carboxyl esterase that hydrolyzes high density lipoproteins, emulsifies triglycerides, is essential for the efficient digestion of dietary fats and can bind to heparin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EDL; Endothelial cell-derived lipase; Endothelial lipase; lipase, endothelial; lipoprotein lipase H; Phospholipase A1; PL
Gene Aliases: EDL; EL; LIPG; PRO719; UNQ387/PRO719
UniProt ID: (Human) Q9Y5X9
Entrez Gene ID: (Human) 9388
lipid metabolic process
response to nutrient
cell proliferation
phospholipid catabolic process
positive regulation of high-density lipoprotein particle clearance
positive regulation of cholesterol transport
high-density lipoprotein particle remodeling
cholesterol homeostasis
reverse cholesterol transport
lipid digestion
regulation of lipoprotein metabolic process
phospholipid homeostasis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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