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Invitrogen
LIPG Polyclonal Antibody
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Product Details
PA1-16799
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
An N-terminal synthetic peptide made to human Endothelial Lipase.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.01% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody does not react with mouse samples.
Target Information
LIPG (Lipase G, Endohelial type) is an endothelial lipase which is a novel member of the lipoprotein lipase gene family. LIPG is synthesized by endothelial cells and functions at the site of synthesis. LIPG most likely plays a physiological role in modulating lipoprotein metabolism. Overexpressed LIPG has been shown to reduce HDL cholesterol levels, whereas an LIPG deficiency appears to be effective in elevating HDL cholesterol levels in animals. LIPG has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. Also, LIPG is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. LIPG is a carboxyl esterase that hydrolyzes high density lipoproteins, emulsifies triglycerides, is essential for the efficient digestion of dietary fats and can bind to heparin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: EDL; Endothelial cell-derived lipase; Endothelial lipase; lipase, endothelial; lipoprotein lipase H; Phospholipase A1; PL
Gene Aliases: EDL; EL; LIPG; PRO719; UNQ387/PRO719
UniProt ID: (Human) Q9Y5X9
Entrez Gene ID: (Human) 9388
lipid metabolic process
response to nutrient
cell proliferation
phospholipid catabolic process
positive regulation of high-density lipoprotein particle clearance
positive regulation of cholesterol transport
high-density lipoprotein particle remodeling
cholesterol homeostasis
reverse cholesterol transport
lipid digestion
regulation of lipoprotein metabolic process
phospholipid homeostasis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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