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Invitrogen
LLGL2 Polyclonal Antibody
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FIGURE: 1 / 1
LLGL2 Antibody (PA5-120204) in WB
Western blot analysis of LLGL2 in extracts of various cell lines. Samples were incubated with LLGL2 Polyclonal antibody (Product # PA5-120204) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
Product Details
PA5-120204
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 938-1027 of mouse LLGL2 (NP_6634132)
Conjugate
Form
Liquid
Concentration
0.96 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive test controls include: Mouse lung, Mouse testis, Rat lung. The target is usually found in the following locations: Cytoplasm.
Immunogen sequence: DSTKAKKHNR PSNGNGTGLK MTSSGHVRNS KSQSDGDEKK PGPVMEHALL NDAWVLKEIQ STLEGDRRSY GNWHPHRVAV GCRLSNGEAE
Target Information
LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Lethal giant larvae-like protein 2; Lethal(2) giant larvae protein homolog 2; LLGL scribble cell polarity complex component 2
Gene Aliases: 9130006H11Rik; Llgl2; Llglh2; RGD1560307
UniProt ID: (Mouse) Q3TJ91
Entrez Gene ID: (Rat) 360661, (Mouse) 217325
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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