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Product Details
PA5-53452
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human LMBR1
Conjugate
Unconjugated
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2643400
Product Specific Information
Immunogen sequence: FTVMGQLLVK PTILEDLDEQ IYIITLEEEA LQRRLNGLSS SVEYNIMELE QELENVKTLK TKLERRKKAS AWERN
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
Target Information
This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Differentiation-related gene 14 protein; FLJ11665; limb region 1 homolog; Limb region 1 protein homolog
Gene Aliases: ACHP; C7orf2; DIF14; LMBR1; LSS; PPD2; THYP; TPT; ZRS
UniProt ID: (Human) Q8WVP7
Entrez Gene ID: (Human) 64327
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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