A suggested positive control is human brain tissue lysate.
PA5-21061 can be used with blocking peptide PEP-1175.
LMBRD1, also known as NESI (nuclear export signal-interacting protein, is a lysosomal membrane protein that is thought be involved in the transport and metabolism of cobalamin. LMBRD1 was initially identified as interacting with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F (cblF).
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Protein Aliases: BM-021, C6orf209, LMBD1, NESI; HDAg-L-interacting protein NESI; hepatitis delta antigen-L interacting protein; liver regeneration p-53 related protein; LMBR1 domain-containing protein 1; Nuclear export signal-interacting protein; Probable lysosomal cobalamin transporter; Protein N90b
Gene Aliases: 0910001K20Rik; AV347960; BM-021; C6orf209; CD001; LMBD1; LMBRD1; MAHCF; MSTP044; NESI