Immunogen sequence: KGTRSAAYER LENTEDIEEV EQHIQTIKSK SKDGRPLPAR DKRALKQFEE RLRTLKKRER HLEFIENSWW TKFCGALRP
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 91%.
LMBRD1, also known as NESI (nuclear export signal-interacting protein, is a lysosomal membrane protein that is thought be involved in the transport and metabolism of cobalamin. LMBRD1 was initially identified as interacting with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F (cblF).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HDAg-L-interacting protein NESI; hepatitis delta antigen-L interacting protein; liver regeneration p-53 related protein; LMBR1 domain-containing protein 1; Nuclear export signal-interacting protein; Probable lysosomal cobalamin transporter
Gene Aliases: BM-021; C6orf209; CD001; LMBD1; LMBRD1; MAHCF; MSTP044; NESI
UniProt ID: (Human) Q9NUN5
Entrez Gene ID: (Human) 55788