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Invitrogen
LMO2 Recombinant Rabbit Monoclonal Antibody (PD00-25)
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FIGURE: 1 / 4
LMO2 Antibody (MA5-50737) in IHC (P)
Immunohistochemistry of LMO2 in paraffin-embedded human lymph node tissue. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 2 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with LMO2 recombinant monoclonal antibody (Product # MA5-50737) with a dilution of 1:2,000 for 1 hour at... View More
Product Details
MA5-50737
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
PD00-25
Immunogen
Recombinant protein full length human LMO2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive control: K562 cell lysates, mouse brain tissue, human tonsil tissue, human lymph nodes tissue.
Predicted band size: 18 kDa
Subcellular Location: Nucleus.
Target Information
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cysteine-rich protein TTG-2; LIM domain only protein 2; LIM only 2; LMO-2; Rhombotin-2; rhombotin-like 1; T-cell translocation gene 2; T-cell translocation protein 2; TTG-2a/RBTN-2a; TTG2/RBTN2
Gene Aliases: LMO-2; LMO2; Rbtn-2; RBTN2; RBTNL1; Rhom-2; RHOM2; TTG2
UniProt ID: (Human) P25791, (Mouse) P25801
Entrez Gene ID: (Human) 4005, (Mouse) 16909
transcription cofactor binding
transcription coactivator activity
protein binding
identical protein binding
bHLH transcription factor binding
metal ion binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
DNA-binding transcription factor binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
RNA polymerase II activating transcription factor binding
transcriptional activator activity, RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
zinc ion binding
cofactor binding
E-box binding
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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