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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 15 amino acid synthetic peptide near the carboxy terminus of human LNPEP|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||20 ug/mL|
|Immunohistochemistry (IHC)||20 ug/ml|
|Western Blot (WB)||1 ug/mL|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control is human lung tissue lysate.
PA5-34458 can be used with blocking peptide PEP-1500.
LNPEP, also known as insulin-responsive aminopeptidase (IRAP), was initially identified as an abundant protein that is associated with specialized endosomes termed GLUT4 storage vesicles (GSVs) in adipocytes. The luminal domain of LNPEP contains an aminopeptidase activity that is involved in peptide hormone processing and antigenic peptide processing. LNPEP is also a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to the GSVs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
angiotensin 4 receptor; angiotensin IV receptor; AT (4) receptor; cystinyl aminopeptidase; gp160; insulin-regulated aminopeptidase; insulin-regulated membrane aminopeptidase; insulin-responsive aminopeptidase; IRAP; Leucyl/cystinyl amino peptidase; leucyl/cystinyl aminopeptidase; LNPEP; otase; oxytocinase; P-LAP; placental leucine aminopeptidase; PLAP; vasopressinase; vp160
CAP; IRAP; LNPEP; OTASE; P-LAP; PLAP