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Invitrogen
LOR Polyclonal Antibody
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FIGURE: 1 / 1
LOR Antibody (PA5-34945) in IHC, ICC/IF
International journal of molecular sciences 2018 -
Figure 5 Immunolocalization of proteins in ( a , c , e ) non-glycated and ( b , d , f ) glycated RHS. Glycated RHS showed ( a , b ) loricrin upregulation, ( c , d ) filaggrin downregulation and slight increase in beta1-integrin expression, and ( e , f ) slight upregulation of both receptor of AGEs (RAGE) and laminin-5 expression compared with non-glycated RHS. Proteins in green or red, cell nuclei (DAPI sta... View More
Product Details
PA5-34945
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide contains a sequence corresponding to a region within amino acids 248 and 312 of Loricrin
Conjugate
Form
Liquid
Concentration
1 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
Product Specific Information
Recommended positive controls: 293T, A431, HeLa, HepG2.
Predicted reactivity: Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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