Keep as concentrated solution.
Positive Control: HeLa, MDA-MB-231, U87-MG, SK-N-SH, SK-N-AS, 293T transfected with LOXL2, mouse lung.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: LOR2 antibody; LOXL2 antibody; Lysyl oxidase homolog 2; lysyl oxidase homolog 2 antibody; lysyl oxidase related 2; lysyl oxidase related 2 antibody; lysyl oxidase-like 2 antibody; lysyl oxidase-like 2 delta e13; lysyl oxidase-like 2 protein; Lysyl oxidase-like protein 2; lysyl oxidase-like protein 2 antibody; Lysyl oxidase-related protein 2; lysyl oxidase-related protein 2 antibody; Lysyl oxidase-related protein WS9-14; lysyl oxidase-related protein WS9-14 antibody; WS9-14 antibody
Gene Aliases: 1110004B06Rik; 4930526G11Rik; 9430067E15Rik; LOR2; LOXL2; WS9-14