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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • EDG4 Antibodies

          Bioss

          LPA2 Polyclonal Antibody

          View all (14) EDG4 antibodies

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          Cite LPA2 Polyclonal Antibody

          • Antibody Testing Data (3)
          LPA2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          LPA2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          LPA2 Antibody (BS-10368R) in IHC (P)

          Formalin-fixed and paraffin embedded rat spleen labeled with Rabbit Anti-LPA2 Polyclonal Antibody, Unconjugated (bs-10368R) at 1:200 followed by conjugation to the secondary antibody and DAB staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          LPA2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          LPA2 Antibody in Western Blot (WB)
          LPA2 Antibody in Flow Cytometry (Flow)
          LPA2 Polyclonal Antibody

          Product Details

          BS-10368R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:500
          -

          Flow Cytometry (Flow)

          1:100
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human LPA2, amino acids 1-100.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Edg4 is a Lysophospholipid/Lysosphingolipid Receptor activated by phosphatidic acid (PA) and lysophosphatidic acid (LPA). It enhances the transcription of serum response element (SRE) reporter genes. In CD4(+) T cells, Edg4 may be involved in the control of interleukin-2 secretion. Edg4 expression has been documented in leukocytes, pancreas, spleen, thymus, prostate, and testis. Edg4 expression has also been seen in many cancer cell lines, including those of brain, blood, breast, ovary, cervix, colon, skin, and thyroid. ESTs have been isolated from B-cell/lung/testis, blood, brain, embryo, heart/melanocyte/uterus, liver, placenta, prostate, and skin libraries.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 4; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4; G protein-coupled receptor; LPA receptor 2; LPA receptor EDG4; LPA-2; LPA2 Receptor; Lysophosphatidic acid receptor 2; Lysophosphatidic acid receptor Edg-4; lysophosphatidic acid receptor EDG4; pre-B-cell leukemia transcription factor 4

          View more View less

          Gene Aliases: EDG-4; EDG4; IPA2; LPA-2; LPA2; Lpar2; Pbx4; RGD1561336

          View more View less

          UniProt ID: (Mouse) Q9JL06

          View more View less

          Entrez Gene ID: (Human) 9170, (Rat) 498609, (Mouse) 53978

          View more View less

          Function(s)
          G-protein coupled receptor activity protein binding lipid binding lysophosphatidic acid receptor activity PDZ domain binding G-protein coupled receptor
          Process(es)
          G-protein coupled receptor signaling pathway activation of phospholipase C activity positive regulation of cytosolic calcium ion concentration activation of MAPK activity positive regulation of Rho protein signal transduction positive regulation of MAPK cascade
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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