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Invitrogen
LPAR4 Polyclonal Antibody
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FIGURE: 1 / 1
LPAR4 Antibody (PA5-120689) in WB
Western blot analysis of LPAR4 in extracts of various cell lines. Samples were incubated with LPAR4 Polyclonal antibody (Product # PA5-120689) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-120689
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 311-370 of human LPAR4 (Q99677).
Conjugate
Form
Liquid
Concentration
0.14 mg/mL
Amount
14 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive test controls include: HeLa, SH-SY5Y, Mouse ovary, Mouse brain, Rat brain.
Immunogen sequence: YYFTLESFQK SFYINAHIRM ESLFKTETPL TTKPSLPAIQ EEVSDQTTNN GGELMLESTF
Target Information
EDG4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG4 is expressed in testes, ovarian tumor, and leukocyte containing tissues.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G protein-coupled receptor 23; G-protein coupled receptor 23; G-protein-coupled receptor; LPA receptor 4; LPA-4; LPA4 Receptor; Lysophosphatidic acid receptor 4; P2Y purinoceptor 9; P2Y5-like receptor; P2Y9; Purinergic receptor 9; unnamed protein product
Gene Aliases: 5730485F04Rik; GPR23; LPA4; LPAR4; P2RY9; P2Y5-LIKE; P2Y9; RGD1563686
UniProt ID: (Human) Q99677, (Mouse) Q8BLG2
Entrez Gene ID: (Human) 2846, (Rat) 302378, (Mouse) 78134
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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