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Invitrogen
LPHN2 Polyclonal Antibody
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Product Details
PA5-33906
Product Specifications
Species Reactivity
Bat,
Bovine,
Dog,
Horse,
Human,
Mouse,
Pig,
Rabbit,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human LPHN2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The Latrophilin family of G protein-coupled receptors consists of three members, latrophilin-1, 2 and 3, each of which displays distinct tissue distribution and function. Latrophilin-1, the most characterized member of this family, acts as a receptor for a-latrotoxin, a component of venom from the black widow spider. Binding of a-latrotoxin to latrophilin-1 triggers synaptic vesicle exocytosis via both Ca2+-dependent and -independent mechanisms, resulting in vesicle depletion. Latrophilin-1 is abundant in brain and present in endocrine cells. Latrophilin-3 is also brain-specific, whereas latrophilin-2 expression is ubiquitous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adhesion G protein-coupled receptor L2; Calcium-independent alpha-latrotoxin receptor 2; calcium-independent alpha-latrotoxin receptor homolog 2; CIRL-2; Cl2aa; latrophilin 1; latrophilin 2; Latrophilin homolog 1; Latrophilin-2; lectomedin 2; Lectomedin-1
Gene Aliases: ADGRL2; AI450192; Cirl-2; CIRL2; CL2; Cl2ac; Gm619; KIAA0786; LEC1; LEC2; LPH2; LPHH1; LPHN2; mKIAA0786
UniProt ID: (Human) O95490, (Bovine) O97817, (Rat) O88923
Entrez Gene ID: (Horse) 100052932, (Rabbit) 100343149, (Human) 23266, (Dog) 490193, (Bovine) 281278, (Pig) 100524685, (Mouse) 99633, (Rat) 171447
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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