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Invitrogen
LPL Polyclonal Antibody
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Product Details
PA5-85126
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chicken,
Human,
Mouse,
Sheep
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human LPL. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.11 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol, 1% BSA
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (90%), Rat (90%), Cat (94%), Pig (93%), Rabbit (92%), Sheep (91%), Bovine (91%), Guinea pig (86%).
Positive Control: Molt-4, NIH-3T3.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: adipose lipoprotein lipase; alpha lipase; Lipoprotein lipase; LPL; O 1-4-5; Phospholipase A1; triacylglycerol lipase
Gene Aliases: HDLCQ11; LIPD; LPL
UniProt ID: (Chicken) P11602, (Human) P06858, (Sheep) Q29524, (Mouse) P11152
Entrez Gene ID: (Chicken) 396219, (Human) 4023, (Sheep) 443408, (Mouse) 16956
lipoprotein lipase activity
phospholipase activity
triglyceride lipase activity
receptor binding
calcium ion binding
heparin binding
phosphatidylcholine 1-acylhydrolase activity
lipase activity
apolipoprotein binding
protein homodimerization activity
heparan sulfate proteoglycan binding
phosphatidylserine 1-acylhydrolase activity
1-acyl-2-lysophosphatidylserine acylhydrolase activity
lipoprotein particle binding
protein binding
triglyceride binding
hydrolase activity
carboxylic ester hydrolase activity
lipase
fatty acid metabolic process
fatty acid biosynthetic process
response to bacterium
positive regulation of macrophage derived foam cell differentiation
positive regulation of cholesterol storage
positive regulation of sequestering of triglyceride
lipid catabolic process
triglyceride catabolic process
cellular response to nutrient
chylomicron remodeling
very-low-density lipoprotein particle remodeling
cholesterol homeostasis
positive regulation of fat cell differentiation
positive regulation of inflammatory response
low-density lipoprotein particle mediated signaling
triglyceride homeostasis
cellular response to fatty acid
positive regulation of chemokine secretion
positive regulation of tumor necrosis factor secretion
retinoid metabolic process
triglyceride metabolic process
phospholipid metabolic process
response to cold
response to glucose
triglyceride biosynthetic process
lipoprotein metabolic process
response to drug
lipid metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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