MA5-15503 targets LPL in WB applications and shows reactivity with Human samples.
The MA5-15503 immunogen is purified recombinant fragment of LPL expressed in E. Coli.
MA5-15503 detects LPL which has a predicted molecular weight of approximately 53.1kDa.
LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
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Protein Aliases: HDLCQ11; LIPD; Lipoprotein lipase; LPL
Gene Aliases: HDLCQ11; LIPD; LPL
UniProt ID: (Human) P06858
Entrez Gene ID: (Human) 4023