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          • Primary Antibodies ›
          • PPAP2C Antibodies

          Bioss

          LPP2 Polyclonal Antibody

          View all (6) PPAP2C antibodies

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          Cite LPP2 Polyclonal Antibody

          Additional Information:
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          LPP2 Polyclonal Antibody

          Product Details

          BS-8527R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          Assay-dependent
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:500
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human VANGL1/LPP2, amino acids 151-250.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Phosphatidic acid phosphatase type 2 (PAP2) was originally identified as a plasma membrane enzyme that catalyses the dephosphorylation of the putative second messenger, phosphatidic acid (PA) to diacylglycerol (DG). Subsequently, multiple isoforms of PAP2 were cloned [2-5]. It was found that these enzymes dephosphorylate a number of lipid phosphates in vitro other than PA, including the potent bioactive lipids, lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P). Therefore, they have been renamed lipid phosphate phosphatases (LPPs). Currently, there are four members of this family called LPP1, LPP1a, LPP2 and LPP3.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Lipid phosphate phosphohydrolase 2; LPR3; PAP-2c; PAP2-G; PAP2-gamma; PAP2c; Phosphatidate phosphohydrolase type 2c; Phosphatidic acid phosphatase 2c; phosphatidic acid phosphatase type 2C; phosphatidic acid phosphohydrolase type 2c; Phospholipid phosphatase 2; PRG-2; PRG2; type-2 phosphatidic acid phosphatase-gamma

          View more View less

          Gene Aliases: LPP2; PAP-2c; PAP2-G; PAP2-gamma; PAP2c; PLPP2; PPAP2C

          View more View less

          UniProt ID: (Human) O43688, (Mouse) Q9DAX2, (Rat) Q8K593

          View more View less

          Entrez Gene ID: (Human) 8612, (Mouse) 50784, (Rat) 246115

          View more View less

          Function(s)
          protein binding phosphatidate phosphatase activity hydrolase activity sphingosine-1-phosphate phosphatase activity ceramide-1-phosphate phosphatase activity phosphatase
          Process(es)
          lipid metabolic process phospholipid metabolic process sphingosine metabolic process ceramide metabolic process signal transduction sphingolipid catabolic process phospholipid dephosphorylation dephosphorylation
          It has to be done as per old AB suggested Products section.

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