Immunogen sequence: KGTQGSPSKPK PEDPRGVPLM AFPRIESPLE TLSAQNHSAS MTEVT
Highest antigen sequence identity to the following orthologs - mouse 98%, rat 98%.
This gene encodes a member of the plasticity-related gene (PRG) family. Members of the PRG family mediate lipid phosphate phosphatase activity in neurons and are known to be involved in neuronal plasticity. The protein encoded by this gene does not perform its function through enzymatic phospholipid degradation. This gene is strongly expressed in brain. It shows dynamic expression regulation during brain development and neuronal excitation. Alternatively spliced transcript variants encoding the same protein have been observed.
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Protein Aliases: Lipid phosphate phosphatase-related protein type 1; Phospholipid phosphatase-related protein type 1; plasticity related gene 3; Plasticity-related gene 3 protein; PRG-3
Gene Aliases: LPPR1; PLPPR1; PRG-3; PRG3
UniProt ID: (Human) Q8TBJ4
Entrez Gene ID: (Human) 54886
Molecular Function: phosphatase