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Invitrogen
LRBA Polyclonal Antibody
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Product Details
PA5-54837
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human LRBA. Recombinant protein control fragment (Product #RP-92443).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GGWRVWVDTL SITHSKVTFE IHKENLANIF REQQGKVDEE IGLCSSTSVQ AASGIRRDIN VSVGSQQPDT KDSPVCPHFT TNGNENSSIE KTSSLESASN IELQTTNTSY EEMKAEQENQ ELPDEGTLEE TL
Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 65%.
Target Information
The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beige-like protein; CDC4-like protein; Lipopolysaccharide-responsive and beige-like anchor protein; LPS-responsive vesicle trafficking, beach and anchor containing; vesicle trafficking, beach and anchor containing
Gene Aliases: BGL; CDC4L; CVID8; LAB300; LBA; LRBA
UniProt ID: (Human) P50851
Entrez Gene ID: (Human) 987
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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