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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
LRIG1 protein Q96JA1 is coded by a gene on a chromosome band 3p14.3, this region is known to be deleted in various human cancers. LRIG1 is considered to be a tumor suppressor gene in humans. LRIG1 is an integral cell-surface membrane protein that is expressed by specific cells in various human tissues and that its 143-kDa form might be cleaved into 111-kDa and 32-kDa fragments. The LRIG1 protein may inhibit the growth of tumors of glial cells and the down-regulation of the LRIG1 gene may be involved in the development and progression of the tumor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp586O1624; integral membrane glycoprotein; leucine-rich repeat protein LRIG1; leucine-rich repeats and immunoglobulin like domains 1; leucine-rich repeats and immunoglobulin-like domains 1; Leucine-rich repeats and immunoglobulin-like domains protein 1; LIG-1; ortholog of mouse integral membrane glycoprotein LIG-1
Gene Aliases: D6Bwg0781e; Img; LIG-1; LIG1; LRIG1
UniProt ID: (Human) Q96JA1, (Mouse) P70193
Entrez Gene ID: (Human) 26018, (Mouse) 16206
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