This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Mouse LRP1.
The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: A2MR; alpha 2-macroglobulin receptor; Alpha-2-macroglobulin receptor; APR; CD91; FLJ16451; IGFBP3R; lipoprotein receptor-related protein; Low-density lipoprotein receptor-related protein 1 515 kDa subunit; Low-density lipoprotein receptor-related protein 1 85 kDa subunit; Low-density lipoprotein receptor-related protein 1 intracellular domain; LRP-1; LRP-515; LRP-85; lrp1; LRPICD; MGC88725; Prolow-density lipoprotein receptor-related protein 1; TGFBR5
Gene Aliases: A2mr; AI316852; b2b1554Clo; CD91; Lrp; Lrp1
UniProt ID: (Mouse) Q91ZX7
Entrez Gene ID: (Mouse) 16971