LRP5/LRP6 Polyclonal Antibody

protein binding coreceptor activity Wnt-protein binding toxin transporter activity Wnt-activated receptor activity low-density lipoprotein receptor activity receptor binding frizzled binding kinase inhibitor activity protein serine/threonine kinase inhibitor activity identical protein binding protein homodimerization activity molecular_function apolipoprotein binding coreceptor activity involved in Wnt signaling pathway transmembrane signal receptor apolipoprotein

gastrulation with mouth forming second vasculature development positive regulation of mesenchymal cell proliferation osteoblast development glucose catabolic process amino acid transport endocytosis nervous system development mesodermal cell migration cholesterol metabolic process regulation of blood pressure positive regulation of cell proliferation organ morphogenesis tissue development anterior/posterior pattern specification gene expression Wnt signaling pathway osteoblast proliferation positive regulation of osteoblast proliferation somatic stem cell population maintenance limb morphogenesis extracellular matrix-cell signaling cell migration involved in gastrulation cholesterol homeostasis embryonic digit morphogenesis regulation of apoptotic process response to peptide hormone small molecule metabolic process positive regulation of cell differentiation positive regulation of fat cell differentiation regulation of osteoblast differentiation negative regulation of osteoblast differentiation positive regulation of osteoblast differentiation positive regulation of cell cycle positive regulation of mitotic nuclear division positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter bone remodeling blood vessel morphogenesis bone marrow development anatomical structure regression retina morphogenesis in camera-type eye canonical Wnt signaling pathway bone development bone morphogenesis branching involved in mammary gland duct morphogenesis mammary gland duct morphogenesis adipose tissue development cell-cell signaling involved in mammary gland development establishment of blood-brain barrier regulation of insulin secretion involved in cellular response to glucose stimulus retina vasculature development in camera-type eye retina vasculature morphogenesis in camera-type eye retinal blood vessel morphogenesis regulation of biological quality cell-cell adhesion Norrin signaling pathway apoptotic process involved in patterning of blood vessels establishment of blood-retinal barrier regulation of transcription, DNA-templated positive regulation of cytosolic calcium ion concentration chemical synaptic transmission neural crest formation neural crest cell differentiation vesicle-mediated transport midbrain development negative regulation of smooth muscle cell apoptotic process chordate embryonic development anatomical structure formation involved in morphogenesis transmembrane transport cellular response to cholesterol dopaminergic neuron differentiation protein localization to plasma membrane midbrain dopaminergic neuron differentiation regulation of ossification embryonic limb morphogenesis Wnt signaling pathway involved in dorsal/ventral axis specification regulation of fat cell differentiation regulation of bone remodeling embryonic camera-type eye morphogenesis positive regulation of sequence-specific DNA binding transcription factor activity embryonic retina morphogenesis in camera-type eye regulation of canonical Wnt signaling pathway negative regulation of protein serine/threonine kinase activity multicellular organism development somitogenesis neural tube closure negative regulation of protein phosphorylation heart looping morphogenesis of an epithelium pericardium morphogenesis axis elongation negative regulation of protein kinase activity embryonic pattern specification dorsal/ventral axis specification single organismal cell-cell adhesion cerebellum morphogenesis thalamus development cerebral cortex cell migration forebrain radial glial cell differentiation forebrain generation of neurons Wnt signaling pathway involved in forebrain neuroblast division neural tube development formation of radial glial scaffolds cerebral cortex development negative regulation of Wnt signaling pathway forebrain development midbrain-hindbrain boundary development embryonic forelimb morphogenesis embryonic hindlimb morphogenesis external genitalia morphogenesis post-anal tail morphogenesis regulation of cell proliferation odontogenesis of dentin-containing tooth positive regulation of apoptotic process negative regulation of fat cell differentiation positive regulation of ossification positive regulation of bone resorption generation of neurons skeletal system morphogenesis negative regulation of epithelial cell proliferation response to folic acid palate development convergent extension regulation of cell development face morphogenesis trachea cartilage morphogenesis mammary placode formation canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation primitive streak formation receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport Wnt signaling pathway involved in somitogenesis axis elongation involved in somitogenesis positive regulation of canonical Wnt signaling pathway toxin transport negative regulation of non-canonical Wnt signaling pathway positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis negative regulation of planar cell polarity pathway involved in pericardium morphogenesis negative regulation of planar cell polarity pathway involved in neural tube closure receptor-mediated endocytosis