Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: YVFPIQTLDC KRKELKKVPN NIPPDIVKLD LSYNKINQLR PKEFEDVHEL
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%
Leucine-rich repeat-containing protein 17 (LRRC17) is an LRR protein predominantly expressed by osteoblasts. LRRC17 acts as a negative regulator of receptor activator of NF-kappaB ligand (RANKL)-induced osteoclast differentiation. It has been reported that low plasma level of LRRC17 is an independent risk factor for osteoporotic fractures.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 37 kDa leucine-rich repeat (LRR) protein; Leucine-rich repeat-containing protein 17; p37NB
Gene Aliases: LRRC17; P37NB; UNQ3076/PRO9909
UniProt ID: (Human) Q8N6Y2
Entrez Gene ID: (Human) 10234
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