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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||18 amino acid peptide near the carboxy terminus of human LRRC26|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A recommended positive control is human prostate tissue lysate.
The LRRC26 protein was initially identified as a cytokeratin-associated protein whose expression was elevated in multiple cancer cell lines and cancer specimens as well in normal prostate and salivary gland tissues. LRRC26 was later found to negatively regulate the NF-kappaB activation and suppresses tumor growth and metastasis. LRRC26 can also act to selectively alter the efficacy of large conductance calcium-activated K (BK) channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
bA350O14.10; BK channel auxiliary gamma subunit LRRC26; BK channel auxilliary gamma subunit LRRC26; CAPC; cytokeratin associated protein; cytokeratin-associated protein in cancer
bA350O14.10; CAPC; LRRC26