Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: PEVCTCVPGG LASCSALSLP AVPPGLSLRL RALLLDHNRV RA
Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 67%.
The LRRC26 protein was initially identified as a cytokeratin-associated protein whose expression was elevated in multiple cancer cell lines and cancer specimens as well in normal prostate and salivary gland tissues. LRRC26 was later found to negatively regulate the NF-kappaB activation and suppresses tumor growth and metastasis. LRRC26 can also act to selectively alter the efficacy of large conductance calcium-activated K (BK) channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BK channel auxiliary gamma subunit LRRC26; BK channel auxilliary gamma subunit LRRC26; cytokeratin associated protein; Cytokeratin-associated protein in cancer; Leucine-rich repeat-containing protein 26
Gene Aliases: bA350O14.10; CAPC; LRRC26
UniProt ID: (Human) Q2I0M4
Entrez Gene ID: (Human) 389816
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