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LRRC8B Antibody (PA5-112101) in WB
Western Blot analysis of LRRC8B using LRRC8B Polyclonal Antibody (Product # PA5-112101) at a dilution of 1:500. Lane A: NCI-H292 whole cell lysate, (Lysates/proteins at 30 µg per lane). The secondary antibody used was a Goat Anti-Rabbit IgG (H&L)/Dylight 800 at 1:10,000 dilution. Developed using the Odyssey technique and performed under reducing conditions. Predicted band size: 92 kDa. Observed band size: 92 kDa.
Product Details
PA5-112101
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to the center region of the Human LRRC8B
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2866837
Product Specific Information
This antibody reacts with: Human, Mouse (Species predicted to react based on 100% sequence homology).
Target Information
Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: leucine rich repeat containing 8 family, member B; leucine-rich repeat containing 8 family member B; Leucine-rich repeat-containing protein 8B; T cell activation leucine repeat rich protein; T-cell activation leucine repeat-rich protein; TA-LRRP; Volume-regulated anion channel subunit LRRC8B
Gene Aliases: KIAA0231; LRRC8B; TA-LRRP; TALRRP; UNQ6413/PRO21207
UniProt ID: (Human) Q6P9F7
Entrez Gene ID: (Human) 23507
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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