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Proteintech
LRRC8D Polyclonal Antibody
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Product Details
11537-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LRRC8D Fusion Protein Ag2138 (515-858 aa encoded by BC024159)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This LRRC8D antibody does not cross-react with LRRC8A.
Immunogen sequence: LQELHLCHC PAKVEQTAFS FLRDHLRCLH VKFTDVAEIP AWVYLLKNLR ELYLIGNLNS ENNKMIGLES LRELRHLKIL HVKSNLTKVP SNITDVAPHL TKLVIHNDGT KLLVLNSLKK MMNVAELELQ NCELERIPHA IFSLSNLQEL DLKSNNIRTI EEIISFQHLK RLTCLKLWHN KIVTIPPSIT HVKNLESLYF SNNKLESLPV AVFSLQKLRC LDVSYNNISM IPIEIGLLQN LQHLHITGNK VDILPKQLFK CIKLRTLNLG QNCITSLPEK VGQLSQLTQL ELKGNCLDRL PAQLGQCRML KKSGLVVEDH LFDTLPLEVK EALNQDINIP FANGI (515-858 aa encoded by BC024159)
Target Information
Component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8D constitutes a pore-forming subunit or whether it is closely associated with the pore.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: HsLRRC8D; leucine rich repeat containing 5; leucine rich repeat containing 8 family; leucine rich repeat containing 8 family, member D; leucine rich repeat containing 8D; leucine-rich repeat containing 8 family member D; leucine-rich repeat-containing 5; Leucine-rich repeat-containing protein 5; Leucine-rich repeat-containing protein 8D; Volume-regulated anion channel subunit LRRC8D
Gene Aliases: 2810473G09Rik; 4930525N13Rik; A930019F03; LRRC5; LRRC8D; UNQ213/PRO239
UniProt ID: (Human) Q7L1W4, (Mouse) Q8BGR2, (Rat) Q5U308
Entrez Gene ID: (Human) 55144, (Mouse) 231549, (Rat) 305131
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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