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Abnova
LRRFIP1 Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 2
LRRFIP1 Antibody (H00009208-D01P) in WB
Western Blot analysis of LRRFIP1 expression in transfected 293T cell line (H00009208-T02) by LRRFIP1 MaxPab polyclonal antibody.
Lane 1: LRRFIP1 transfected lysate(12.20 KDa).
Lane 2: Non-transfected lysate.
Lane 1: LRRFIP1 transfected lysate(12.20 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00009208-D01P
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LRRFIP1 (AAH10662.1, 1 a.a. approximately 105 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Amount
100 µg
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MHVMDLQRDA NRQISDLKFK LAKSEQEITA LEQNVIRLES QVSRYKSAAE NAEKIEDELK AEKRKLQREL RSALDKTEEL EVSNGHLVKR LEKMKANRSA LLSQQ
Target Information
Leucine-rich repeat FLI-I interacting protein 1 (LRRFIP1/FLAP-1) is a MyD88-interacting signal protein which mediates either induction or repression of TLR signaling. Flap-1 directly interacts with β-catenin and activates β-catenin-dependent transcription activity. Flap-1 or LRRFIP1 was also shown to bind the TNF- -308 promoter polymorphism site, suggesting its possible role in the regulation of TNF- production. FLAP-1 along with LRRFIP2 and FLIIH serve as a balance in coordinating inflammatory response after infection, and may act as a novel target in the control of agonist-induced TLR-mediated inflammatory and autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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